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Studies & Reviews

Want to Improve Medication Adherence? Educate Patients Now

Dr. Dylan Steen, director of clinical trials and population health research at the University of Cincinnati Division of Cardiovascular Health and Disease, co-presented a scientific paper about the efficacy of statins in controlling cholesterol in high-risk patients. Among Steen’s findings were that statin utilization among patients with coronary heart disease, peripheral artery disease, ischemic stroke, type 2 diabetes and other conditions that raise the risk of heart attack was unacceptably low, particularly in the U.S.

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Medisafe Reveals That Users of Its Medication Management Platform Lower Their Blood Pressure with High Clinical Significance

Medisafe, the leading mHealth platform for medication management with over 2 million users, announced today the results of its blood pressure study: app users with stage 1 or stage 2 hypertension decreased their systolic blood pressure by 17.7 and 25.3 mmHg respectively within 30 days.

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New CVS Health Research Pinpoints Tendency Toward Non-Adherence

A new study by researchers at the CVS Health Research Institute and Brigham and Women's Hospital provides evidence that patients' patterns of medication fills in the first few months after starting on a chronic therapy accurately predict future medication adherence behavior. The study, published in The American Journal of Managed Care, suggests that this approach may help quickly identify those patients most likely to benefit from medication adherence interventions.

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Recognizing the Hospital’s Role in Changing Patient Behavior

Article in Becker's Hospital Review about ways health care facilities can encourage medication adherence to prevent readmissions.

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Preventing Readmissions Through Improved Medication Management

In an article previously published to Case Management Insider Health Leaders Media discusses how medication adherence can prevent hospital readmissions. They elaborate on the cost of poor medication adherence, as well as the acronym SIMPLE that is aimed to help providers gain better adherence.

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For Many Reasons, Patients Choose to Skip Medications

The Durango Herald highlights the endless struggle between physicians and patients who do not take their medication. The article cites cost as one of many reasons why patients are resist medication adherence, as well as how providers and health systems contribute to the issue.

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How Do Generic Drug Appearances Affect Patient Adherence?

Pharmacy Times reports the FDA is looking to survey pharmacists and patients to see how patients adhere to existing treatment based on changes in medications' color, shape, and size. Researchers expect patients to be more likely to stop taking medication when physical attributes change.

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Oral MS Drugs May Not Automatically Boost Adherence

Oral drugs for multiple sclerosis (MS) may not improve adherence over injectables as they were expected to do, according to several studies. Three recent studies examined the relationship between drug administration pathways (oral, injectable, etc.) and adherence.

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Adherence Aiding Solutions: Scalable, Meaningful, and Affordable

The importance of adherence, developing an adherence platform and how health care organizations should harness technology to boost medication adherence.

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Pharmacist intervention improves diabetes of underserved patients

Underserved patients with suboptimally controlled type 2 diabetes exhibited greater medication adherence and better glycemic control with pharmacist-directed medication management than with usual care, according to recent study findings published in The Diabetes Educator.

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Informed Engagement: Unpacking and Addressing Patients’ Reasons for Nonadherence

Given that adherence is such a personal issues with various causing, one expert in the field questions why we've been approaching it from a systems efficiency perspective. After outlining taxonomy of terminology of the problem, public awareness can be increased, and pharmacists can begin engaging patients to curb this epidemic.

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FDA Studying How Generics’ Size, Shape and Color Impact Medication Adherence

Given recent research on how the appearance of medications impacts their use, the FDA just approved a formal study of how the size, shape, and color of a medication impacts medications adherence. While the FDA can't control a generic drug's appearance, it can help inform strategies "that pharmacists use to inform patients when the appearance of their medications change."

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Adherence Technology: Numerous Health Behavior Theories Must Be Incorporated Into Interventions

Thomas Morrow, MD, outlines the common barriers to adherence, saying that despite the number of adherence solutions targeting forgetfulness, this is only a small percentage of the reason people don't take their medication. He also outlines major theories of health behavior which could help explain this reasoning behind nonadherence.

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Medication Adherence Pays Off for Patients, Payers, and Community Pharmacy

At the most recent APhA meeting in San Diego, community pharmacists discussed the impacts of offering adherence solutions on their bottom line. According to one pharmacist, "For every dollar we spend on medication adherence in diabetes, the healthcare system saves $7." Better managing transitions of care can help ensure adherence in complex patients.

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Non-Adherence In Health Care: Are Patients Or Policy Makers Ill-Informed?

A Chicago economist discusses the difference between under-adherence and over-adherence to treatments. While most interventions focus on under-adherence, the author argues that over-adherence to the wrong therapy is just as damaging. "Personalized medicine is, as a result, actually a critical tool for attaining appropriate levels of adherence."

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Diabetes-specific, Employee-based Health Plan Helps People Manage Their Treatment Better

A recent study shows that people enrolled in a health plan tailored to their specific medical condition are more likely to stick to their medication and actively take charge of their own health care. For the Diabetes Health Plan, patients were 5% more likely to adhere to their medications than on a standard health plan.

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Adherence vs. Persistence

For the past year, pharmacists at Towncrest Pharmacy have been working with a payer to evaluate how community pharmacists can impact adherence. In the evaluation, researchers differentiated compliance (adherence) from persistence, or the length of time until a patient discontinues therapy. Towncrest pharmacists advocate for continuous medication monitoring (CMM) w/ check-ins at every refill.

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Adherence to blood thinner best with pharmacist management, researcher says

New research from the Stanford University School of Medicine shows that adherence to blood-thinners was best when pharmacists were involved in the management of care. Patients in the Veterans Health Administration who received education and regular pharmacist monitoring were 80% more likely to adhere to medication guidelines than those who didn’t receive this kind of support.

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Ask the Right Questions to Improve Medication Adherence

A recent study evaluated 29 different approaches to increasing medication adherence among a group of over 6,500 heart failure patients. The researchers determined interventions that focused on changing patient behavior were more effective than those centered on teaching patients about their medications.

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Medication Adherence Low in Diabetes

In a large cohort of patients with diabetes, rates of adherence for both statins and ACE inhibitors were “alarmingly low” at 34%, with nonadherent patients experiencing a higher rate of major adverse cardiac events (MACE), researchers reported at the American College of Cardiology (ACC) Scientific Sessions 2015.

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Health System Factors Improve Medication Adherence Among Seniors with Diabetes

Specific system-level factors controlled by health care systems – including prescriptions with a medication supply greater than 90 days, mail-order pharmacy use, and lower copayments and out-of-pocket maximums – nearly doubled the likelihood that patients adhered to prescribed heart and diabetes medications, according to a study published in the journal Medical Care.

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Meta-analysis of trials of interventions to improve medication adherence

A.M. Peterson, et al. studied the literature from 1966 to December 2000 on the effectiveness of tools and methods to enhance medication adherence.

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Medication Adherence Leads To Lower Health Care Use And Costs Despite Increased Drug Spending Roebuck

M. Christopher Roebuck, et al. examined the relationship between improved medication adherence and reduced total healthcare use and costs.

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Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost

Michael C. Sokol, et al. evaluated the impact of medication adherence on healthcare use and costs for four chronic conditions.

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Medication Adherence: WHO Cares?

Marie T. Brown and Jennifer K. Bussell reviewed the literature published between January 1990 and March 2010 on general aspects of medication adherence pertaining to cardiovascular disease.

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Interventions for enhancing medication adherence (Review)

Brian Haynes, et al. summarized the results of randomized controlled trials of medication adherence interventions.

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Medication Therapy Management Interventions in Outpatient Settings

This study concluded that the evidence base offers low evidence of benefit for a limited number of intermediate and health utilization outcomes.

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